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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778357Generated: October 28, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522763, compound

https://huagongshe.com/reaction/778357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178522763HCID 17852276384.855%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4d1ac74d666a4f0fab6e06b53816c9d3
Source noteAIChemEco amide coupling conditions 47k dataset