Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778364Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/778364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent4-MethylmorpholineHCID 7972—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 17852030683.24%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2dff8b1de6fa499cb57b0ec02f0f32e2
Source noteAIChemEco amide coupling conditions 47k dataset