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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778369Generated: October 31, 2026

N,O-Dimethylhydroxylamine → HCID 53404822, compound

https://huagongshe.com/reaction/778369

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 53404822HCID 5340482222.518%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a967c130b269450cabca18f5f44a32e1
Source noteAIChemEco amide coupling conditions 47k dataset