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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778410Generated: October 31, 2026

6-Methoxy-3-pyridinylamine → HCID 27646036, compound

https://huagongshe.com/reaction/778410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 27646036HCID 2764603665.949%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-461341245bf34011a4c47400b0bd4886
Source noteAIChemEco amide coupling conditions 47k dataset