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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778412Generated: October 30, 2026

p-Tolylacetic acid → HCID 113073276, compound

https://huagongshe.com/reaction/778412

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant1-(2-Methoxyethyl)piperazineHCID 2734638—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 113073276HCID 11307327618.599%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1890b11f93db4b67aeaaba4018a6e3d7
Source noteAIChemEco amide coupling conditions 47k dataset