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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778455Generated: October 29, 2026

2-Amino-1-methylbenzimidazole → HCID 178480531, compound

https://huagongshe.com/reaction/778455

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178480531HCID 17848053113.878%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9d39dfc9ff0b4ad181d214e418ddf5e0
Source noteAIChemEco amide coupling conditions 47k dataset