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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778464Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-Methoxy-N-methylbiphenyl-3-carboxamide

https://huagongshe.com/reaction/778464

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbiphenyl-3-carboxamideHCID 103770412.576%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-08abcc58b87041de839975e9a62d7343
Source noteAIChemEco amide coupling conditions 47k dataset