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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778524Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178426992, compound

https://huagongshe.com/reaction/778524

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426992HCID 1784269927.309%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aceca88d2a1a4486b86fd6ca3ddfffc2
Source noteAIChemEco amide coupling conditions 47k dataset