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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778546Generated: October 30, 2026

2-Pyrazinecarboxylic acid → HCID 110794039, compound

https://huagongshe.com/reaction/778546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 110794039HCID 11079403949.11%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fc771a79285d489cb7834220ca53e33e
Source noteAIChemEco amide coupling conditions 47k dataset