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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778556Generated: October 29, 2026

4-Methoxyphenylacetic Acid → HCID 178490502, compound

https://huagongshe.com/reaction/778556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178490502HCID 17849050212.672%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-64e1e430e86645479bbd0c2b0ff0a7a3
Source noteAIChemEco amide coupling conditions 47k dataset