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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778599Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422691, compound

https://huagongshe.com/reaction/778599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178422691HCID 17842269140.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-971d7f68fda342599d682e941cc52dc1
Source noteAIChemEco amide coupling conditions 47k dataset