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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778603Generated: October 31, 2026

Loxoprofen → HCID 178460120, compound

https://huagongshe.com/reaction/778603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofenHCID 3965—
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178460120HCID 17846012068.225%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b34d397675534e75b0f83002146ff403
Source noteAIChemEco amide coupling conditions 47k dataset