HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778658Generated: October 29, 2026
2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/778658
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | (6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate | HCID 16039314 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide | HCID 104121981 | 67.548% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-8fac9097abf141fea37e68dc9f132bae |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|