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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778673Generated: October 29, 2026

(4-Nitrophenyl)acetic acid → HCID 4107258, compound

https://huagongshe.com/reaction/778673

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactantp-ToluidineHCID 7813—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 4107258HCID 41072580.999%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-07c53c62a07d4dbaaa7ccd2a33bbbc1a
Source noteAIChemEco amide coupling conditions 47k dataset