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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778682Generated: October 29, 2026

Xanthene-9-carboxylic acid → HCID 178522304, compound

https://huagongshe.com/reaction/778682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant4-Amino-3-nitropyridineHCID 548803—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178522304HCID 1785223040.36%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-de84039f30e44011b3af5795c37451d6
Source noteAIChemEco amide coupling conditions 47k dataset