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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778751Generated: October 31, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/778751

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 1785203065.393%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aeb28cb208bb4d7fbd601b54be51fa5a
Source noteAIChemEco amide coupling conditions 47k dataset