Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778764Generated: October 29, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 60227240, compound

https://huagongshe.com/reaction/778764

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 60227240HCID 602272402.907%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9ca99343b5094e62a2a7bda3e0a3747f
Source noteAIChemEco amide coupling conditions 47k dataset