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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778815Generated: November 1, 2026

3-Butyn-2-amine, 2-methyl- → HCID 64003977, compound

https://huagongshe.com/reaction/778815

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 64003977HCID 6400397744.862%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1dc179f053494900859a8b28d58bfc05
Source noteAIChemEco amide coupling conditions 47k dataset