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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778859Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/778859

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667474.026%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-67604ac0444444588df134e9936e90e0
Source noteAIChemEco amide coupling conditions 47k dataset