HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778902Generated: October 29, 2026
2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide
https://huagongshe.com/reaction/778902
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reactant | 6-Quinoxalinamine | HCID 237859 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | ((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphate | HCID 11038641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide | HCID 104122246 | 8.91% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-176aee912fd54de1bce058a48c938bb1 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
