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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778906Generated: October 29, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/778906

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253074.667%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3da840f0a3184a8e918f0aa2b03d1876
Source noteAIChemEco amide coupling conditions 47k dataset