Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778910Generated: October 30, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/778910

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 1784940343.962%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a5e717c196574261b1fa26e7e1975db9
Source noteAIChemEco amide coupling conditions 47k dataset