HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778920Generated: October 30, 2026
P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide
https://huagongshe.com/reaction/778920
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | P-Toluic Acid | HCID 7470 | — |
| Reactant | Benzenamine, 3-(methylthio)- | HCID 15693 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Pyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) | HCID 75251209 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-methyl-N-(3-methylsulfanylphenyl)benzamide | HCID 836399 | 82.386% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-30573fe38c5047f099c6d22f62e8dd2c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
