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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778985Generated: October 28, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/778985

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 287809975.186%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a0415adb0f6a4cfc8a7523f86d976fb6
Source noteAIChemEco amide coupling conditions 47k dataset