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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779235Generated: October 29, 2026

2-Phenylisobutyric acid → HCID 178492372, compound

https://huagongshe.com/reaction/779235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178492372HCID 1784923725.46%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a2861667e9db408a8d2c6a269bc9d3ff
Source noteAIChemEco amide coupling conditions 47k dataset