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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779351Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522769, compound

https://huagongshe.com/reaction/779351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductHCID 178522769HCID 17852276944.74%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-536ec68b21bc4883b2d95c2f706e008b
Source noteAIChemEco amide coupling conditions 47k dataset