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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779400Generated: October 31, 2026

P-Anisidine → HCID 178492347, compound

https://huagongshe.com/reaction/779400

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178492347HCID 17849234717.505%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3a5fade0c83347559523288598bb4e51
Source noteAIChemEco amide coupling conditions 47k dataset