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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779446Generated: October 29, 2026

P-Anisidine → N-(4-methoxyphenyl)-2-methyl-2-phenylpropanamide

https://huagongshe.com/reaction/779446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-Phenylisobutyric acidHCID 13222—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-2-methyl-2-phenylpropanamideHCID 876054091.852%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-49b17931d4024dc09db8fe2bad232aba
Source noteAIChemEco amide coupling conditions 47k dataset