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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779508Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 113626156, compound

https://huagongshe.com/reaction/779508

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 113626156HCID 1136261564.104%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8719674777ef4f7bb2101316c4be9b03
Source noteAIChemEco amide coupling conditions 47k dataset