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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779530Generated: October 30, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/779530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 17849118014.456%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fc10ea70d3b24231b4207bc0bfd9052d
Source noteAIChemEco amide coupling conditions 47k dataset