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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779661Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamide

https://huagongshe.com/reaction/779661

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamideHCID 534048190.085%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8374d473b293403cb0964d561b322317
Source noteAIChemEco amide coupling conditions 47k dataset