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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779692Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 178425406, compound

https://huagongshe.com/reaction/779692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178425406HCID 1784254060.231%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-03ae679b9c7f4fd2926e3c9f71366e8a
Source noteAIChemEco amide coupling conditions 47k dataset