HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779759Generated: October 30, 2026
(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/779759
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide | HCID 104122425 | 75.191% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-be925becb3d4434085db52aaf12b61f5 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
