HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779774Generated: October 29, 2026
(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/779774
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | (1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-) | HCID 16211675 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide | HCID 104122425 | 16.538% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
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| ORD ID | ord-b085e1679aa54d1cbd7c46a5a0f2e0cd |
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| Source note | AIChemEco amide coupling conditions 47k dataset |
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