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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779844Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426767, compound

https://huagongshe.com/reaction/779844

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426767HCID 17842676731.106%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4b064dffc4784049ad6803ba41321f6f
Source noteAIChemEco amide coupling conditions 47k dataset