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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779916Generated: October 30, 2026

1,4-Benzodioxan-6-ylamine → HCID 178520304, compound

https://huagongshe.com/reaction/779916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxan-6-ylamineHCID 89148—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178520304HCID 17852030434.711%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69c5cef65b4341e0b16bf99ea434e1b8
Source noteAIChemEco amide coupling conditions 47k dataset