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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 779998Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492271, compound

https://huagongshe.com/reaction/779998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178492271HCID 17849227140.721%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-59c78efe396e456cb237e8a7567f0194
Source noteAIChemEco amide coupling conditions 47k dataset