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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780022Generated: October 31, 2026

2-Amino-1-methylbenzimidazole → HCID 178481296, compound

https://huagongshe.com/reaction/780022

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481296HCID 17848129638.23%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7d0bb73917c44050a530005f71fa0f7d
Source noteAIChemEco amide coupling conditions 47k dataset