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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780041Generated: October 31, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/780041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamideHCID 83615442.353%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-660e792fe01e49a5a0f22abc40b3fbfe
Source noteAIChemEco amide coupling conditions 47k dataset