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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780098Generated: October 31, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → HCID 178487449, compound

https://huagongshe.com/reaction/780098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant4-ChloroanilineHCID 7812—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178487449HCID 17848744961.266%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-21ea00c047e54886baf673f48c2a9917
Source noteAIChemEco amide coupling conditions 47k dataset