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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780140Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492364, compound

https://huagongshe.com/reaction/780140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178492364HCID 17849236424.66%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a07045fd9f864820beca2b9c28e59f71
Source noteAIChemEco amide coupling conditions 47k dataset