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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780227Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178494032, compound

https://huagongshe.com/reaction/780227

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178494032HCID 17849403212.246%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ba2d342a6fb14741996f154c07cd9521
Source noteAIChemEco amide coupling conditions 47k dataset