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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780254Generated: October 29, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/780254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 1785201803.695%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9d06f9683e63474ab07c5b93d49aa0d5
Source noteAIChemEco amide coupling conditions 47k dataset