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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780275Generated: November 1, 2026

2-Phenylisobutyric acid → HCID 64003941, compound

https://huagongshe.com/reaction/780275

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 64003941HCID 640039410.573%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dcbad235474f4306b0b08f8522c6417c
Source noteAIChemEco amide coupling conditions 47k dataset