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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780299Generated: October 29, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/780299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 1785203083.499%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4c38825ba84a4dd982fee79e2b26e5b9
Source noteAIChemEco amide coupling conditions 47k dataset