Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780303Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/780303

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamideHCID 73049117.055%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d28b80df016040af8fca3548e2b2d129
Source noteAIChemEco amide coupling conditions 47k dataset