4-((E)-2-furan-2-yl-vinyl)benzoic acid ethyl ester → 4-(2-(Tetrahydrofuran-2-yl)-ethyl)-benzoic acid ethyl ester

Participants

Reaction Steps

To an anhydrous tetrahydrofuran (25 mL) solution of 4-((E)-2-furan-2-yl-vinyl)-benzoic acid ethyl ester (2.2 g, 9.39 mmol) described in Manufacturing Example 80-1-1 was added 10% palladium-carbon (50% hydrate, 1 g), which was stirred for 6 hours under hydrogen atmosphere at room temperature. The reaction liquid was filtered, and the filtrate was concentrated under a reduced pressure to obtain the title compound (2.2 g, 100%) as a crude product.

Provenance & Evidence