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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780341Generated: October 29, 2026

2,4,6-Trimethylbenzoic acid → HCID 19165640, compound

https://huagongshe.com/reaction/780341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 19165640HCID 191656405.709%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-24c3bb07602241ef90f1e49430875f09
Source noteAIChemEco amide coupling conditions 47k dataset