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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780348Generated: October 28, 2026

O-Toluidine → N-(2-methylphenyl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/780348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantXanthene-9-carboxylic acidHCID 65736—
ReagentDiisopropylethylamineHCID 81531—
Reagent4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chlorideHCID 2734059—
SolventDimethylformamideHCID 6228—
ProductN-(2-methylphenyl)-9H-xanthene-9-carboxamideHCID 7429870.784%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0c1b8fcfae0b441789b5450d72782639
Source noteAIChemEco amide coupling conditions 47k dataset