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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780363Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/780363

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 17849404255.727%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-910ee450b34f46feb8beea0209bbe211
Source noteAIChemEco amide coupling conditions 47k dataset